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1. Who among the following scientists had no contribution in the development of the double helix model for the structure of DNA?
A. Meselson and Stahl
B. Rosalind Franklin
C. Erwin Chargaff
D. Maurice Wilkins
2. DNA has genetic properties was revealed for the first time by
A. Chargaff
B. Griffith
C. Avery
D. Wilkins
3. The beginning of understanding genetic transformation in bacteria was made by
A. Hershey and Chase
B. Watson and Crick
C. Frederick Griffith
D. T. H. Morgan
4. DNA contains nucleobases , sugar and phosphate. Removal of which among these from a DNA sample will not significantly affect the length of DNA?
A. Nucleobases
B. Sugar
C. Phosphate
D. None of the above
5. According to Chargaff's rule, which one is correct?
A. [A] + [T] = [G] + [C]
B. [A] + [C] = [G] + [T]
C. [A] + [G] = [T] + [C]
D. All of these
6. Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a triplet?
A. Nirenberg and Matthaei
B. Hershey and Chase
C. Beadle and Tatum
D. Morgan and Sturtevant
7. In Hershey and Chase experiments, radioactive 32P was used to culture bacteriophages which resulted in radioactive
A. Protein capsule of bacteriophage
B. Viral DNA
C. Bacterial capsule
D. Viral proteins
8. Which of the following is a structural subunit of DNA?
A. Nucleotides
B. Carbohydrate
C. Protein
D. RNA
9. Which of the following are the functions of RNA?
A. It is a carrier of genetic information from DNA to ribosomes synthesising polypeptides.
B. It carries amino acids to ribosomes.
C. It is a constituent component of ribosomes.
D. All of the above.
10. While analysing the DNA of an organism, a total number of 5386 nucleotides were found out of which the proportion of different bases were Adenine = 29%, Guanine = 17%, Cytosine = 32% and Thymine = 17%. Considering the Chargaff’s rule, it can be concluded that
A. It is a double-stranded linear DNA.
B. It is single-stranded DNA.
C. No conclusion can be drawn.
D. It is a double-stranded circular DNA.
11. Nitrogenous bases present in DNA:
A. Adenine, guanine, cytosine, thymine
B. Guanine, uracil
C. Adenine, guanine, cytosine, uracil
D. Adenine, thymine, uracil
12. Beadle and Tatum showed that each kind of mutant bread mould they studied lacked a specific enzyme. Their experiments demonstrated that
A. Genes carry information for making proteins.
B. Enzymes are required to repair damage.
C. Cells need specific enzymes in order to function.
D. Genes are made up of DNA.
13. A typical nucleosome contains
A. 100 bp of DNA helix
B. 400 bp of DNA helix
C. 200 bp of DNA helix
D. 300 bp of DNA helix
14. DNA nucleotides are attached by
A. Van der Waals bond
B. Electrovalent bond
C. Hydrogen bond
D. Covalent bond
15. In the DNA molecule,
A. There are two strands which run parallel in the 5'-3' direction.
B. The total amount of purine nucleotides and pyrimidine nucleotides is not always equal.
C. Proportion of adenine in relation to thymine varies with the organism.
D. There are two strands which run antiparallel - one in 5'-3' direction and other in 3'-5' direction.
16. Retroviruses have genetic material
A. DNA only
B. Either DNA or RNA only
C. DNA or RNA only
D. RNA only
17. If the percentage of cytosine is 18%, then the percentage of adenine will be
A. 64%
B. 32%
C. 23%
D. 36%
18. Uracil is present in RNA at the place of
A. Adenine
B. Thymine
C. Guanine
D. Cytosine
19. The genetic material of a viroid is
A. Protein
B. DNA
C. Carbohydrate
D. RNA
20. The net electric charge on DNA and histones is
A. Negative and positive, respectively
B. Both negative
C. Both positive
D. Zero
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